Hannah Yevick Wins Nano-K 2015 Thesis Prize

Congratulations Jeanne Jodin, for publishing her work “Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover” in Developmental Cell. Jeanne showed that stable force balance between cells in a tissue requires robust actin filament turnover. The paper was also highlighted by the journal. Read the paper and the highlight article.

Congratulations to graduate student, Marlis Denk-Lobnig, on passing her qualifying exam.

Congratulations to Soline on publishing her work “Actomyosin Meshwork Mechanosensing Enables Tissue Shape to Orient Cell Force” in Nature Communications. Soline discovered a mechanism by which tissue and organism shape can instruct cells how to generate force. This has implications in understanding how tissues and organs acquire their correct shape.

Congratulations to Soline on publishing her work “Myosin 2-Induced Mitotic Rounding Enables Columnar Epithelial Cells to Interpret Cortical Spindle Positioning Cues” in Current Biology. Soline showed how mitotic cell rounding is critical to orient cell division such that both daughter cells remain in the tissue.

Congratulations to graduate student, Mimi Xie, for her publication “Intracellular signalling and intercellular coupling coordinate heterogeneous contractile events to facilitate tissue folding” in Nature Communications. In the paper, Mimi showed that cells exhibit three classes of contractile events, unconstricting, unratcheted, and ratcheted. Mimi demonstrated that cells undergo transitions between different classes of contractions, going from unconstricting or unratcheted contractions to ratcheted contractions. A transcription factor that regulates this developmental stage is important for the proper order of contractile events. It is important for cells to generate ratcheted contractions because this promotes cooperation between cells.