We have a number of new additions to the lab including postdocs Jasmin Imran Alsous and Nat Clarke, graduate students Anna Yeh and Jaclyn Camuglia, undergraduates Prateek Kalakuntla and Jennifer Nwako, and technician Vardges Tserunyan.
Congratulations Dr. Yeh on defending your PhD and getting a job in industry! We wish her the best of luck.
Congratulations to graduate student, Mimi Xie, for her publication “Intracellular signalling and intercellular coupling coordinate heterogeneous contractile events to facilitate tissue folding” in Nature Communications. In the paper, Mimi showed that cells exhibit three classes of contractile events, unconstricting, unratcheted, and ratcheted. Mimi demonstrated that cells undergo transitions between different classes of contractions, going from unconstricting or unratcheted contractions to ratcheted contractions. A transcription factor that regulates this developmental stage is important for the proper order of contractile events. It is important for cells to generate ratcheted contractions because this promotes cooperation between cells.
Congratulations Soline on the publication of a book chapter Mechanical Force Sensing in Tissues!
Congratulations Frank on publishing his work “LRhoA GTPase Inhibition Organizes Contraction During Epithelial Morphogenesis” in The Journal of Cell Biology! Frank showed how inhibiting RhoA can promote contraction during tissue folding. And read the Spotlight article on our paper, written by Alpha Yap. Also, congratulations on your new position as a Research Assistant Professor at Vanderbilt University!
Congratulations to Soline on publishing her work “Myosin 2-Induced Mitotic Rounding Enables Columnar Epithelial Cells to Interpret Cortical Spindle Positioning Cues” in Current Biology. Soline showed how mitotic cell rounding is critical to orient cell division such that both daughter cells remain in the tissue.
Biology graduate student, Natalie Heer, joins the lab. Natalie received her undergraduate degree from Harvard University where she worked in the Reck-Peterson lab on dynein motility.
