Congratulations postdoc Jasmin Imran Alsous and grad student Jonathan Jackson on publishing their paper titlec Dynamics of hydraulic and contractile wave-mediated fluid transport during Drosophila oogenesis in PNAS.
Congratulations to postdoc, Frank Mason, for the recent publication of his paper, “Apical domain polarization promotes actin-myosin assembly to drive ratchet-like apical constriction” on Nature Cell Biology. In the paper, Mason et al. show that the signals that regulate contractile forces in constricting cells exhibit a spatial organization within the apical domain of the cell. Signals that activate myosin motors are polarized to the center of the apical domain. Actin polymerization in this domain suppresses junctional protein localization, restricting junctional proteins to cell-cell interfaces. Thus, a “radial” cell polarity is established, which is shown to be important for apical constriction.
Biology graduate student, Clint Ko, is joining our lab. Clint was an undergrad at Cornell University where he worked on plant development. We are happy he has turned to the fruit fly for his next system.
Congratulations Jonathan on publishing his work “Apical Sarcomere-like Actomyosin Contracts Nonmuscle Drosophila Epithelial Cells” in Developmental Cell. Jonathan discovered that the apical actin cortex of an epithelial cell can be organized like a muscle sarcomere to promote contraction and tissue folding.
Postdoctoral fellow, Hannah Yevick, published her research titled Structural redundancy in supracellular actomyosin networks enables robust tissue folding in Developmental Cell. You can hear her talk about what she discovered in the video produced by Raleigh McElvery of the MIT Biology department. Read an MIT News article on the research.
We have a number of new additions to the lab including postdocs Jasmin Imran Alsous and Nat Clarke, graduate students Anna Yeh and Jaclyn Camuglia, undergraduates Prateek Kalakuntla and Jennifer Nwako, and technician Vardges Tserunyan.
Congratulations Jaci on a stellar PhD thesis and tour de force paper. We wish her the best of luck on her next position in industry!
