Congratulations Dr. Heer

Congratulations to graduate student, Natalie Heer, for publishing her review article “Tension, Contraction and Tissue Morphogenesis” in Development. Natalie contributed to the special issue celebrating the 100th anniversary of “On Growth and Form.” Her review article describes the latest research explaining how forces are generated to sculpt tissues.

The Martin lab won the coveted group costume competition for the Biology department Halloween party. They had a winning combination of fish-like pillows and various forms of wasabi.

Adam Martin has been promoted to Associate Professor, effective July 1, 2016.

Congratulations to postdoc, Frank Mason, for the recent publication of his paper, “Apical domain polarization promotes actin-myosin assembly to drive ratchet-like apical constriction” on Nature Cell Biology. In the paper, Mason et al. show that the signals that regulate contractile forces in constricting cells exhibit a spatial organization within the apical domain of the cell. Signals that activate myosin motors are polarized to the center of the apical domain. Actin polymerization in this domain suppresses junctional protein localization, restricting junctional proteins to cell-cell interfaces. Thus, a “radial” cell polarity is established, which is shown to be important for apical constriction.

Congratulations Jonathan on publishing his work “Apical Sarcomere-like Actomyosin Contracts Nonmuscle Drosophila Epithelial Cells” in Developmental Cell. Jonathan discovered that the apical actin cortex of an epithelial cell can be organized like a muscle sarcomere to promote contraction and tissue folding.

Congratulations to graduate student, Marlis Denk-Lobnig, who was featured in the MIT Biology department news. Read the article.