Hannah publishes WIREs Developmental Biology review

Congratulations to graduate student, Jonathan Coravos, on passing his qualifying exam.

Congratulations to postdoc, Frank Mason, for the recent publication of his paper, “Apical domain polarization promotes actin-myosin assembly to drive ratchet-like apical constriction” on Nature Cell Biology. In the paper, Mason et al. show that the signals that regulate contractile forces in constricting cells exhibit a spatial organization within the apical domain of the cell. Signals that activate myosin motors are polarized to the center of the apical domain. Actin polymerization in this domain suppresses junctional protein localization, restricting junctional proteins to cell-cell interfaces. Thus, a “radial” cell polarity is established, which is shown to be important for apical constriction.

Congratulations postdoc Jasmin Imran Alsous and grad student Jonathan Jackson on publishing their paper titlec Dynamics of hydraulic and contractile wave-mediated fluid transport during Drosophila oogenesis in PNAS.

Congratulations to graduate student, Clint Ko, on publishing his research titled Microtubules promote intercellular contractile force transmission during tissue folding in the Journal of Cell Biology. Clint discovered that microtubules maintain intercellular adhesion by regulating actin.

Biology student Marlis Denk-Lobnig joins the lab. Marlis did her undergraduate work at Georg-August University in Göttingen, Germany. Marlis is interested in applying computational approaches to studying signaling networks in an embryo.

Graduate student Clint Ko and Undergraduate Prateek Kalakuntla publish MBoC paper on how mitotic entry can repress ‘active’ contractility and result in relaxation that promotes neighboring tissue folding.