Hannah publishes WIREs Developmental Biology review

Congratulations to Soline on publishing her work “Myosin 2-Induced Mitotic Rounding Enables Columnar Epithelial Cells to Interpret Cortical Spindle Positioning Cues” in Current Biology. Soline showed how mitotic cell rounding is critical to orient cell division such that both daughter cells remain in the tissue.

Congratulations to graduate student, Jonathan Jackson, on passing his qualifying exam.

Congratulations to Marlis Denk-Lobnig on a wonderful thesis talk! Marlis is moving on to do a postdoc at the University of Michigan.

Anthony is the newest postdoc in the lab. Anthony comes to us from the MIT Mechanical Engineering PHD program.

Congratulations to graduate student, Mimi Xie, for her publication “Intracellular signalling and intercellular coupling coordinate heterogeneous contractile events to facilitate tissue folding” in Nature Communications. In the paper, Mimi showed that cells exhibit three classes of contractile events, unconstricting, unratcheted, and ratcheted. Mimi demonstrated that cells undergo transitions between different classes of contractions, going from unconstricting or unratcheted contractions to ratcheted contractions. A transcription factor that regulates this developmental stage is important for the proper order of contractile events. It is important for cells to generate ratcheted contractions because this promotes cooperation between cells.