Elena Kingston wins poster prize

Congratulations to postdoc, Frank Mason, for the recent publication of his paper, “Apical domain polarization promotes actin-myosin assembly to drive ratchet-like apical constriction” on Nature Cell Biology. In the paper, Mason et al. show that the signals that regulate contractile forces in constricting cells exhibit a spatial organization within the apical domain of the cell. Signals that activate myosin motors are polarized to the center of the apical domain. Actin polymerization in this domain suppresses junctional protein localization, restricting junctional proteins to cell-cell interfaces. Thus, a “radial” cell polarity is established, which is shown to be important for apical constriction.

Congratulations to graduate student, Clint Ko, on publishing his research titled Microtubules promote intercellular contractile force transmission during tissue folding in the Journal of Cell Biology. Clint discovered that microtubules maintain intercellular adhesion by regulating actin.

Dr. Yevick starts as an Assistant Professor at Brandeis University. Check out her new lab website. Congratulations and good luck, Hannah!

Hannah received her Ph.D. from the Institut Curie in Paris, France. Her Bachelor’s degree is in Physics and she published a really cool paper on cells walking a “tightrope.” She is interested in collective cell behavior changing tissue shape.

Congratulations to graduate student, Natalie Heer, for publishing her review article “Tension, Contraction and Tissue Morphogenesis” in Development. Natalie contributed to the special issue celebrating the 100th anniversary of “On Growth and Form.” Her review article describes the latest research explaining how forces are generated to sculpt tissues.